Almost all cases of chronic fatigue syndrome involve chronic, low-grade inflammation of the intestines. This can be caused by many factors. In chronic inflammation of the intestines, our immune system is constantly active. This consumes a lot of energy, causing fatigue and exhaustion.
Just chronic low-grade inflammation in the gut is not enough to develop chronic fatigue syndrome. There is almost always an acute stress-inducing moment when this condition manifests itself. Common are an infection (bacteria or virus), but also sometimes after acute exhaustion (for example, having performed a very intense or sustained sporting effort with little training).
In acute infections, a functioning immune system is essential. If the immune system is chronically activated, it can be harmful to the body. To kill harmful invaders, the immune system produces toxins. These can also destroy the body’s own cells.
Damage to the body’s own cells then in turn triggers activation of the immune system. Thus a negative spiral is created and this problem maintains itself.
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